Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230481 | 0.84 | STAT3 (0.47) | TRPV1STAT3MCHR1 | |
| SCHEMBL18230521 | 0.81 | TRPV1 (0.59) | TRPV1STAT3 | |
| SCHEMBL18230351 | 0.81 | P2RY14 (0.44) | MPLTRPV1STAT3MCHR1 | |
| SCHEMBL18230421 | 0.78 | ADORA1 (0.62) | MPLTRPV1 | |
| SCHEMBL18230388 | 0.77 | LRRK2 (0.61) | STAT3 | |
| SCHEMBL18230382 | 0.76 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL18230372 | 0.76 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL18230428 | 0.75 | MAPT (0.46) | TRPV1STAT3 | |
| SCHEMBL18230368 | 0.75 | TRPV4 (0.46) | TRPV1STAT3 | |
| SCHEMBL18230311 | 0.74 | STAT3 (0.47) | TRPV1STAT3HDAC4HDAC6MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |