Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230378 | 0.84 | MPL (0.49) | STAT3TRPV1MCHR1 | |
| SCHEMBL18230521 | 0.82 | TRPV1 (0.59) | STAT3TRPV1NPC1RAB9AMEN1 | |
| SCHEMBL18094534 | 0.81 | LMNA (0.55) | STAT3TRPV1DEGS1PTGS1KCNQ3 | |
| SCHEMBL18236300 | 0.81 | GRM1 (0.53) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL18230388 | 0.79 | LRRK2 (0.61) | STAT3MAPTSMN1; SMN2LMNA | |
| SCHEMBL18230428 | 0.78 | MAPT (0.46) | STAT3TRPV1NPC1RAB9AMAPT | |
| SCHEMBL18230351 | 0.78 | P2RY14 (0.44) | STAT3TRPV1MCHR1 | |
| SCHEMBL18230368 | 0.77 | TRPV4 (0.46) | STAT3TRPV1MAPTSMN1; SMN2 | |
| SCHEMBL18230311 | 0.77 | STAT3 (0.47) | STAT3TRPV1DEGS1PTGS1KCNQ3 | |
| SCHEMBL18230382 | 0.77 | TRPV1 (0.53) | TRPV1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |