Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230420 | 0.91 | TRPV4 (0.70) | TRPV4TRPV1ADORA2AADORA1MEN1 | |
| SCHEMBL18230400 | 0.87 | TRPV4 (0.56) | TRPV4TRPV1ADORA2AADORA1MEN1 | |
| SCHEMBL18230473 | 0.80 | TRPV1 (0.50) | TRPV4TRPV1ADORA2AADORA1NPC1 | |
| SCHEMBL18230523 | 0.80 | TRPV1 (0.57) | TRPV1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230379 | 0.80 | ADORA2A (0.71) | TRPV1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230521 | 0.80 | TRPV1 (0.59) | TRPV1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230474 | 0.79 | TRPV1 (0.52) | TRPV4TRPV1ADORA2AADORA1MEN1 | |
| SCHEMBL18230428 | 0.79 | MAPT (0.46) | TRPV1ITKNPC1RAB9AMAPT | |
| SCHEMBL18230280 | 0.79 | TRPV1 (0.58) | TRPV1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230443 | 0.78 | TRPV1 (0.48) | TRPV4TRPV1ADORA2AADORA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |