Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 3/20 | 0.45 |
| ▸ | KDM4B | O94953 | 3/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230233 | 0.93 | ADORA2A (0.48) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230294 | 0.91 | TRPV1 (0.54) | ADORA2AADORA1TRPV4KDM4AKDM4B | |
| SCHEMBL18230513 | 0.90 | TLR7 (0.49) | ADORA2AADORA1DHODHTRPV1SCD | |
| SCHEMBL19638116 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230321 | 0.85 | ADORA2A (0.48) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230254 | 0.85 | TRPV4 (0.52) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18236379 | 0.85 | ADORA2A (0.50) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230439 | 0.85 | LMNA (0.53) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230391 | 0.84 | ADORA2A (0.49) | ADORA2AADORA1DHODHTRPV4KDM4A | |
| SCHEMBL18230296 | 0.83 | TRPV1 (0.54) | ADORA2AADORA1TRPV4KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |