Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230361 | 0.94 | ADORA3 (0.46) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230503 | 0.94 | ADORA2A (0.45) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230513 | 0.93 | TLR7 (0.49) | ADORA2AADORA1TRPV1BRAFP2RX1 | |
| SCHEMBL18230296 | 0.92 | TRPV1 (0.54) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230282 | 0.92 | TRPV4 (0.56) | ADORA2AADORA1TRPV4ADORA3RAF1 | |
| SCHEMBL18230233 | 0.90 | ADORA2A (0.48) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230404 | 0.85 | ADORA2A (0.47) | ADORA2AADORA1TRPV4TRPV1ADORA3 | |
| SCHEMBL18230414 | 0.85 | ADORA2A (0.51) | ADORA2AADORA1TRPV4ADORA3KDM4A | |
| SCHEMBL18230284 | 0.84 | ADORA2A (0.39) | ADORA2AADORA1TRPV4ADORA3MAPT | |
| SCHEMBL18230294 | 0.84 | TRPV1 (0.54) | ADORA2AADORA1TRPV4TRPV1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |