Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230321 | 0.93 | ADORA2A (0.48) | TLR7ADORA2AADORA1LMNADHODH | |
| SCHEMBL18230296 | 0.91 | TRPV1 (0.54) | TLR7ADORA2AADORA1LMNAMAPT | |
| SCHEMBL18230404 | 0.90 | ADORA2A (0.47) | ADORA2AADORA1DHODHMAPTTRPV1 | |
| SCHEMBL18230503 | 0.90 | ADORA2A (0.45) | ADORA2AADORA1LMNAMAPTTRPV1 | |
| SCHEMBL18230361 | 0.90 | ADORA3 (0.46) | TLR7ADORA2AADORA1LMNADHODH | |
| SCHEMBL18230282 | 0.87 | TRPV4 (0.56) | ADORA2AADORA1DHODHBRAFMAPT | |
| SCHEMBL18230324 | 0.87 | TLR7 (0.54) | TLR7ADORA2AADORA1LMNADHODH | |
| SCHEMBL18230507 | 0.87 | PCSK9 (0.48) | TLR7ADORA2AADORA1DHODHBRAF | |
| SCHEMBL19638116 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1DHODHSCDKDM4E | |
| SCHEMBL18230233 | 0.85 | ADORA2A (0.48) | ADORA2AADORA1DHODHMAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |