Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230248 | 0.89 | CES2 (0.53) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL7759502 | 0.84 | HPGD (0.57) | CES2CES1L3MBTL1KDM4EGAA | |
| SCHEMBL18230251 | 0.81 | GRM4 (0.47) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL27686242 | 0.80 | CHRM2 (0.49) | L3MBTL1KDM4EGAAALDH1A1HPGD | |
| SCHEMBL25199297 | 0.80 | POLB (0.57) | L3MBTL1KDM4EGAAHSD17B10GRM5 | |
| SCHEMBL38661644 | 0.79 | CTNNB1 (0.44) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL5443676 | 0.79 | HTR3E (0.44) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL5443678 | 0.79 | HTR3E (0.44) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL408199 | 0.78 | CES2 (0.48) | CES2CES1L3MBTL1KDM4EGAA | |
| SCHEMBL11815953 | 0.77 | ITGB3 (0.61) | L3MBTL1KDM4EGAAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |