Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL439311 | 0.98 | KMT2A (0.47) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL29714884 | 0.90 | CHRNB2 (0.48) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL7449557 | 0.90 | CHRNB2 (0.48) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29714883 | 0.89 | CHRNB2 (0.47) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL6211662 | 0.88 | RIPK1 (0.47) | CYP3A4CYP2C9L3MBTL1LMNACHRNB2 | |
| SCHEMBL5928876 | 0.88 | CES2 (0.57) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| Tert-Butyl Formate SCHEMBL27968885 | 0.85 | RBP4 (0.39) | CES2CES1CYP3A4CYP2C9CHRNB2 | |
| SCHEMBL5042317 | 0.84 | CYP3A4 (0.58) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL6449861 | 0.84 | CYP3A4 (0.58) | CES2CES1CYP3A4CYP2C9L3MBTL1 | |
| SCHEMBL13150579 | 0.83 | CHRNB2 (0.56) | CES2CES1CYP3A4CYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102464894-B | Method for preparing pyrazolone anti-vignetting dye | SHENYANG PHOTOSENSITIVE CHEMICAL RES INST | 2014-05-14 | — | — | CN | claimed |
| CN-102464894-A | Preparation method of pyrazolone antihalation dye | SHENYANG PHOTOSENSITIVE CHEMICAL RES INST | 2012-05-23 | — | — | CN | claimed |
| CN-115850241-B | Substituted heterocyclic compound containing alpha-ketone skeleton and application thereof | 中国药科大学 | 2025-01-14 | — | — | CN | disclosed |
| US-20240391901-A1 | SUBSTITUTED HETEROCYCLIC COMPOUND CONTAINING ALPHA-KETONE FRAMEWORK, AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2024-11-28 | — | — | US | disclosed |
| WO-2023046055-A1 | SUBSTITUTED HETEROCYCLIC COMPOUND CONTAINING α-KETONE FRAMEWORK, AND USE THEREOF | 中国药科大学 | 2023-03-30 | — | — | WO | disclosed |
| CN-115850241-A | Substituted heterocyclic compound containing alpha-ketone skeleton and application thereof | 中国药科大学 | 2023-03-28 | — | — | CN | disclosed |
| US-9212180-B2 | Menin-MLL inhibitors and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-12-15 | — | — | US | disclosed |
| US-9181266-B2 | 2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors | NOVARTIS AG (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9181266-B2 | 2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors | NOVARTIS AG (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9181266-B2 | 2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors | NOVARTIS AG (CH) | 2015-11-10 | — | — | US | disclosed |
| EP-2731942-B1 | NOVEL 2-PIPERIDIN-1-YL-ACETAMIDE COMPOUNDS FOR USE AS TANKYRASE INHIBITORS | NOVARTIS AG (CH) | 2015-09-23 | — | — | EP | disclosed |
| EP-1571145-A1 | Substituted piperidine compounds for use as H3 histamine receptor antagonists | SCHERING CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| US-20040097513-A1 | Novel non-imidazole compounds | ASLANIAN ROBERT G (US) | 2004-05-20 | — | — | US | disclosed |
| US-6720328-B2 | TREATING ALLERGY, ALLERGY-INDUCED AIRWAY RESPONSES, AND CONGESTION (E.G., NASAL CONGESTION) | SCHERING CORPORATION | 2004-04-13 | — | — | US | disclosed |
| CN-1469873-A | Piperidine compounds useful as antiallergic agents | ���鹫˾ | 2004-01-21 | — | — | CN | disclosed |
| EP-1326858-A2 | PIPERIDINE COMPOUNDS AS ANTI-ALLERGIC | Schering Corporation (US) | 2003-07-16 | — | — | EP | disclosed |
| US-20030045519-A1 | Novel non-imidazole compounds | SCHERING CORPORATION | 2003-03-06 | — | — | US | disclosed |
| EP-0958287-B1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002032893-A2 | PIPERIDINE COMPOUNDS AS ANTI-ALLERGIC | SCHERING CORPORATION (US) | 2002-04-25 | — | — | WO | disclosed |
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097513-A1 | Novel non-imidazole compounds | HRH2, HRH1, HRH4 | CES2 3215/4885CES1 2083/4885CYP3A4 802/4885 |
| US-20030045519-A1 | Novel non-imidazole compounds | HRH2, HRH1, HRH4 | CES2 3215/4885CES1 2083/4885CYP3A4 802/4885 |
| US-20240391901-A1 | SUBSTITUTED HETEROCYCLIC COMPOUND CONTAINING ALPHA-KETONE FRAMEWORK, AND USE THEREOF | FAAH, FAAH2, FAH | CES2 978/4885CES1 99/4885CYP3A4 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.