SCHEMBL18233459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16985244	0.83	MKNK1 (0.38)	NPC1HPGDRAB9ASMN1; SMN2CCR2
	SCHEMBL8799954	0.79	CA2 (0.39)	NPC1HPGDRAB9ASMN1; SMN2MEN1
	SCHEMBL8799649	0.74	AHR (0.41)	NPC1RAB9ASMN1; SMN2KMT2ACA2
	SCHEMBL8797911	0.72	CA2 (0.54)	CCR2CA2ARF2RL3PKM
	SCHEMBL720789	0.71	CA2 (0.67)	HPGDSMN1; SMN2CCR2CA2CA12
	SCHEMBL9063028	0.71	CA2 (0.67)	HPGDSMN1; SMN2CCR2CA2CA12
	SCHEMBL2097841	0.68	NPC1 (0.39)	NPC1HPGDRAB9ASMN1; SMN2AR
	SCHEMBL12728518	0.68	CYP1A1 (0.40)	NPC1HPGDRAB9ASMN1; SMN2AR
	SCHEMBL17193877	0.68	NPC1 (0.36)	NPC1HPGDRAB9ASMN1; SMN2MEN1
	SCHEMBL16686379	0.68	CYP2A6 (0.52)	NPC1HPGDRAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.