Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230248 | 0.80 | CES2 (0.53) | L3MBTL1CTNNB1WNT3AALDH1A1SMN1; SMN2 | |
| SCHEMBL13391117 | 0.79 | GPR119 (0.60) | KDM4E | |
| SCHEMBL7759502 | 0.76 | HPGD (0.57) | L3MBTL1CTNNB1WNT3AEPHX2ALDH1A1 | |
| SCHEMBL38661644 | 0.74 | CTNNB1 (0.44) | L3MBTL1CTNNB1WNT3AALDH1A1SMN1; SMN2 | |
| SCHEMBL18230251 | 0.74 | GRM4 (0.47) | L3MBTL1CTNNB1WNT3AALDH1A1RIPK1 | |
| SCHEMBL18230433 | 0.74 | MAOB (0.51) | L3MBTL1CTNNB1WNT3AALDH1A1KDM4E | |
| SCHEMBL4768006 | 0.72 | CYP2C9 (0.64) | CYP2C9CYP2C19GAA | |
| SCHEMBL2224365 | 0.71 | L3MBTL1 (0.69) | L3MBTL1NAMPTEPHX2EPHX1ALDH1A1 | |
| SCHEMBL13913916 | 0.71 | TEAD1 (0.67) | ALDH1A1KDM1A | |
| SCHEMBL12120400 | 0.71 | L3MBTL1 (0.63) | L3MBTL1NAMPTEPHX2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |