Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520293 | 0.94 | ADORA3 (0.71) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL14079473 | 0.89 | ADORA3 (0.64) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL10037041 | 0.89 | ADORA3 (0.68) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL3195987 | 0.89 | ALDH1A1 (0.73) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL12676399 | 0.88 | FAAH (0.74) | FAAHALDH1A1DGKAMGLLGPR55 | |
| SCHEMBL31493299 | 0.87 | ALDH1A1 (0.67) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL9905949 | 0.87 | FAAH (0.82) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL15451530 | 0.87 | FAAH (0.82) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL9905962 | 0.86 | ADORA3 (0.64) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL16994443 | 0.86 | FAAH (0.57) | ADORA3NR1I2PGRPTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016181199-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND GOUT | MOHAN M ALAPATI (IN) | 2016-11-17 | — | — | WO | disclosed |