Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | FAAH | O00519 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18237104 | 0.94 | ADORA3 (0.64) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL14079473 | 0.94 | ADORA3 (0.64) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL10037041 | 0.94 | ADORA3 (0.68) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL3195987 | 0.94 | ALDH1A1 (0.73) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL9905949 | 0.93 | FAAH (0.82) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL15451530 | 0.93 | FAAH (0.82) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL31493299 | 0.93 | ALDH1A1 (0.67) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL9905962 | 0.91 | ADORA3 (0.64) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL19676635 | 0.90 | FAAH (0.74) | ADORA3NR1I2PGRPTGS2PDE4D | |
| SCHEMBL30733166 | 0.90 | FAAH (0.74) | ADORA3NR1I2PGRPTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335140-B1 | SYSTEMS, APPARATUS, AND METHODS FOR ANALYZING AND PREDICTING CELLULAR PATHWAYS | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | ADORA3 112/4885NR1I2 798/4885PGR 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.