SCHEMBL18239160

SCHEMBL18239160

c1ccc(N(c2ccccc2)c2ccc3c(c2)c2ccccc2n2c4ccccc4c4ccc5c6ccccc6n3c5c42)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 6/20 0.36
MAPT P10636 5/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
HPGD P15428 4/20 0.34
HTT P42858 3/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPK1 P28482 1/20 0.34
HBB P68871 1/20 0.34
ATM Q13315 2/20 0.32
NPY5R Q15761 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21710579 0.94 KDM4E (0.38) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL18239163 0.92 TSPO (0.40) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL25880307 0.92 KDM4E (0.35) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL25880327 0.90 ALDH1A1 (0.36) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL14552226 0.90 KDM4E (0.32) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL19770584 0.90 KMT2A (0.37) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL21127163 0.88 KDM4E (0.35) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL21126780 0.87 ALDH1A1 (0.36) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL16842728 0.87 KDM4E (0.38) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL18239161 0.87 TSPO (0.36) KDM4EALDH1A1MAPTTSPOPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021484-B2 Compound including nitrogen and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-01 US disclosed
EP-3460863-A1 COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-03-27 EP disclosed
US-20190084992-A1 COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-21 US disclosed
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-05-31 US disclosed
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-05-31 US disclosed
WO-2016182186-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190084992-A1 COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME OR10J3, L1CAM, NOS1 KDM4E 2890/4885ALDH1A1 781/4885MAPT 3591/4885
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, OPA1, MT-ND4 KDM4E 1270/4885ALDH1A1 481/4885MAPT 559/4885
US-11021484-B2 Compound including nitrogen and organic electroluminescence device including the same OR10J3, L1CAM, NOS1 KDM4E 2890/4885ALDH1A1 781/4885MAPT 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.