Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424587 | 0.77 | RXFP1 (0.54) | KDM4EHPGDSMN1; SMN2RAB9AMAPT | |
| SCHEMBL7205313 | 0.73 | HPGD (0.64) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL12990926 | 0.72 | KDM4E (0.59) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL5191625 | 0.71 | KDM4E (1.00) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL1905100 | 0.70 | KDM4E (0.53) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL5717746 | 0.70 | KDM4E (0.74) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL9376353 | 0.70 | NPC1 (0.57) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL29163011 | 0.70 | HTT (0.60) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL13768213 | 0.70 | HPGD (0.60) | KDM4EGAAHPGDHTTSMN1; SMN2 | |
| SCHEMBL10988973 | 0.69 | HPGD (0.55) | KDM4EGAAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053175-B2 | Thioether compounds as nitrification inhibitors | BASF SE (DE) | 2021-07-06 | — | — | US | disclosed |
| US-20180134633-A1 | THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2018-05-17 | — | — | US | disclosed |
| US-20180134633-A1 | THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2018-05-17 | — | — | US | disclosed |
| WO-2016180859-A1 | THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS | BASF SE (DE) | 2016-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053175-B2 | Thioether compounds as nitrification inhibitors | TST, NOS1, NAT1 | KDM4E 2059/4885GAA 3068/4885HPGD 682/4885 |
| US-20180134633-A1 | THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS | TST, NOS1, NAT1 | KDM4E 2059/4885GAA 3068/4885HPGD 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.