Sugi Predict

Sugi Predict / Compounds / SCHEMBL18239273

SCHEMBL18239273

SCHEMBL18239273

COc1ccc2c(C#Cc3c4ccccc4c(C#Cc4cccc5cc(OC)ccc45)c4cc(C)ccc34)cccc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.41
▸ CYP2A6 P11509 1/20 0.41
▸ ACHE P22303 1/20 0.38
▸ IDH1 O75874 1/20 0.37
▸ CNR2 P34972 1/20 0.36
▸ GRM5 P41594 1/20 0.36
▸ CYP11B1 P15538 2/20 0.36
▸ CYP11B2 P19099 2/20 0.36
▸ DHFR P00374 1/20 0.36
▸ CHAT P28329 1/20 0.35
▸ CYP2D6 P10635 2/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2B6 P20813 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449071 0.92 CYP1A2 (0.49) CYP1A2CYP2A6CNR2CYP11B1CYP11B2
SCHEMBL25057147 0.86 CYP1A2 (0.41) CYP1A2CYP2A6CNR2CYP11B1CYP11B2
SCHEMBL16925648 0.86 CYP1A2 (0.41) CYP1A2CYP2A6CYP11B1CYP11B2DHFR
SCHEMBL19449089 0.84 CYP1A2 (0.39) CYP1A2CYP2A6CYP11B1CYP11B2DHFR
SCHEMBL23169140 0.84 CYP1A2 (0.42) CYP1A2CYP2A6CYP11B1CYP11B2DHFR
SCHEMBL21697436 0.80 MTNR1A (0.39) IDH1MTNR1AMTNR1B
SCHEMBL19452973 0.79 TDP1 (0.54) ACHEGRM5TDP1L3MBTL1
SCHEMBL20042831 0.78 ACACB (0.38) CYP1A2CYP2A6CNR2CYP2D6MTNR1A
SCHEMBL18251573 0.76 ACACB (0.35) CYP1A2CYP2A6CNR2CYP2D6MEN1
SCHEMBL18251427 0.76 ACACB (0.34) CYP1A2CYP2A6CNR2CYP2D6MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018159-B2 Ultra bright dimeric or polymeric dyes and methods for preparation of the same Sony Group Corporation (JP) 2024-06-25 — — US disclosed
EP-3294811-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY GROUP CORP (JP) 2024-02-28 — — EP disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
EP-4137818-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2023-02-22 — — EP disclosed
US-20220402963-A1 NUCLEOTIDE PROBES Sony Group Corporation (JP) 2022-12-22 — — US disclosed
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE Sony Group Corporation (JP) 2022-07-14 — — US disclosed
US-11370922-B2 Ultra bright polymeric dyes with peptide backbones SONY CORPORATION (JP) 2022-06-28 — — US disclosed
US-20220168435-A1 PROGRAMMABLE POLYMERIC DRUGS SONY CORPORATION (JP) 2022-06-02 — — US disclosed
US-20220160887-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-05-26 — — US disclosed
US-11312736-B1 Programmable polymeric drugs SONY CORPORATION (JP) 2022-04-26 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
WO-2017214165-A1 IONIC POLYMERS COMPRISING FLUORESCENT OR COLORED REPORTER GROUPS SONY CORPORATION (JP) 2017-12-14 — — WO disclosed
WO-2017197144-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY CORPORATION (JP) 2017-11-16 — — WO disclosed
WO-2017197014-A2 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF SONY CORPORATION (JP) 2017-11-16 — — WO disclosed
WO-2017196954-A1 ULTRA BRIGHT POLYMERIC DYES WITH PEPTIDE BACKBONES SONY CORPORATION (JP) 2017-11-16 — — WO disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
WO-2017177065-A2 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — WO disclosed
WO-2017173348-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH RIGID SPACING GROUPS SONY CORPORATION (JP) 2017-10-05 — — WO disclosed
WO-2017173355-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY CORPORATION (JP) 2017-10-05 — — WO disclosed
WO-2016183185-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY CORPORATION (JP) 2016-11-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402963-A1 NUCLEOTIDE PROBES METTL3, SNRPA, L3MBTL3 CYP1A2 4154/4885CYP2A6 2845/4885ACHE 1357/4885
US-11312736-B1 Programmable polymeric drugs NCL, PBRM1, LPXN CYP1A2 3967/4885CYP2A6 3435/4885ACHE 993/4885
US-20220160887-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, NCL, PBRM1 CYP1A2 3954/4885CYP2A6 3586/4885ACHE 716/4885
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE H1-0, POLM, H1-2 CYP1A2 4067/4885CYP2A6 2992/4885ACHE 1214/4885
US-20220168435-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, PBRM1, CHRM2 CYP1A2 3864/4885CYP2A6 3225/4885ACHE 351/4885
US-11370922-B2 Ultra bright polymeric dyes with peptide backbones IK, NGLY1, MRPL21 CYP1A2 4671/4885CYP2A6 4869/4885ACHE 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.