Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21796145 | 0.98 | CYP4Z1 (0.43) | CYP4Z1NOS1TLR8TLR7GNAI3 | |
| SCHEMBL854766 | 0.86 | — | — | |
| SCHEMBL515050 | 0.73 | CYP4Z1 (0.37) | CYP4Z1TLR8ALDH1A1TSHRGNAI3 | |
| SCHEMBL7600953 | 0.72 | CYP4Z1 (0.40) | CYP4Z1ALDH1A1TSHRGNAI3GNAO1 | |
| SCHEMBL1445010 | 0.71 | ALDH1A1 (0.40) | CYP4Z1NOS1ALDH1A1TSHRGNAI3 | |
| SCHEMBL6594115 | 0.70 | HPGD (0.40) | NOS1ALDH1A1 | |
| SCHEMBL8138858 | 0.70 | CYP4Z1 (0.49) | CYP4Z1ASAH1NAAA | |
| SCHEMBL3183421 | 0.69 | CYP1A2 (0.36) | CYP4Z1TLR8TLR7ALDH1A1TSHR | |
| SCHEMBL10685285 | 0.69 | ALDH1A1 (0.45) | NOS1TLR8TLR7ALDH1A1TSHR | |
| SCHEMBL22267930 | 0.69 | ALDH1A1 (0.45) | NOS1TLR8TLR7ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792844-B | Combination of an anti-FGFR 2 antibody and another agent | 第一三共株式会社 | 2021-03-02 | — | — | CN | claimed |
| EP-3056215-B1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO CO LTD (JP) | 2019-11-20 | — | — | EP | claimed |
| US-9931401-B2 | Combination comprising anti-fibroblast growth factor receptor 2 (FGFR2) antibody and a tyrosine kinase inhibitor | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-03 | — | — | US | claimed |
| US-20160317656-A1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-11-03 | — | — | US | claimed |
| EP-3056215-A1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-08-17 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-3517535-B1 | ALKYNYL-SUBSTITUTED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |
| CN-105792844-B | Combination of an anti-FGFR 2 antibody and another agent | 第一三共株式会社 | 2021-03-02 | — | — | CN | disclosed |
| EP-3056215-B1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO CO LTD (JP) | 2019-11-20 | — | — | EP | disclosed |
| US-9931401-B2 | Combination comprising anti-fibroblast growth factor receptor 2 (FGFR2) antibody and a tyrosine kinase inhibitor | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-03 | — | — | US | disclosed |
| US-20160317656-A1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-11-03 | — | — | US | disclosed |
| EP-3056215-A1 | COMBINATION OF ANTI-FGFR2 ANTIBODY AND OTHER AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-1896395-B1 | MODIFIED MALONATE DERIVATIVES | MERCK SHARP & DOHME (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6593477-B1 | Synthesis of 3-acylaminopyrazoles | EASTMAN KODAK COMPANY | 2003-07-15 | — | — | US | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0129830-B1 | N-ALKYLAMINOPYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND HERBICIDES CONTAINING THE SAME | SDS Biotech K.K. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4545809-A | Herbicidal N-(5-t-butyl-3-pyrazolyl) carbamates | SDS BIOTECH K.K. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4505739-A | Herbicidal 5-t-butyl-3-(N-alkanoylamino)pyrazoles | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-03-19 | — | — | US | disclosed |
| EP-0129830-A2 | N-alkylaminopyrazole derivatives, process for preparing the same, and herbicides containing the same | SDS Biotech K.K. (JP) | 1985-01-02 | — | — | EP | disclosed |