SCHEMBL21796145

SCHEMBL21796145

CCCCCCNn1cccn1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 5/20 0.43
NOS1 P29475 2/20 0.38
GNAI3 P08754 1/20 0.36
GNAO1 P09471 1/20 0.36
GNAI1 P63096 1/20 0.36
NAAA Q02083 2/20 0.36
EPHX1 P07099 1/20 0.35
ASAH1 Q13510 1/20 0.35
TLR8 Q9NR97 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
TBXAS1 P24557 1/20 0.34
DNM2 P50570 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824038 0.98 CYP4Z1 (0.41) CYP4Z1NOS1GNAI3GNAO1GNAI1
SCHEMBL854766 0.84
SCHEMBL7600953 0.74 CYP4Z1 (0.40) CYP4Z1GNAI3GNAO1GNAI1NAAA
SCHEMBL515050 0.72 CYP4Z1 (0.37) CYP4Z1GNAI3GNAO1GNAI1NAAA
SCHEMBL28655496 0.71 ALDH1A1 (0.45) NOS1TLR8TLR7TBXAS1
SCHEMBL22267930 0.71 ALDH1A1 (0.45) NOS1TLR8TLR7TBXAS1
SCHEMBL10685285 0.71 ALDH1A1 (0.45) NOS1TLR8TLR7TBXAS1
SCHEMBL1445010 0.70 ALDH1A1 (0.40) CYP4Z1NOS1GNAI3GNAO1GNAI1
SCHEMBL5358426 0.70 EPHX1 (0.42) CYP4Z1GNAI3GNAO1GNAI1NAAA
SCHEMBL1964419 0.70 EPHX1 (0.42) CYP4Z1GNAI3GNAO1GNAI1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP disclosed