Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 5/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12154245 | 0.81 | KMT2A (0.48) | KMT2ACES2CES1GPR139ALDH1A1 | |
| SCHEMBL8309337 | 0.81 | NR4A2 (0.52) | KMT2ACES1GPR139ALDH1A1SMN1; SMN2 | |
| SCHEMBL6057351 | 0.81 | KMT2A (0.50) | KMT2ACES2CES1GPR139ALDH1A1 | |
| SCHEMBL16047247 | 0.80 | KMT2A (0.52) | KMT2ACES2CES1GPR139ALDH1A1 | |
| SCHEMBL18244312 | 0.79 | MAPT (0.55) | KMT2ACES1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL18113163 | 0.78 | POLB (0.49) | KMT2AALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL7290449 | 0.78 | KMT2A (0.45) | KMT2ACES2CES1GPR139ALDH1A1 | |
| SCHEMBL6057163 | 0.78 | ALDH1A1 (0.57) | KMT2ACES2CES1GPR139ALDH1A1 | |
| SCHEMBL18243806 | 0.77 | AKT1 (0.50) | KMT2AGPR139ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1641518 | 0.77 | HDAC3 (0.55) | KMT2ACES2CES1GPR139ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567297-B2 | Method for synthesizing of thioesters by using compound as catalyst | NATIONAL CENTRAL UNIVERSITY (TW) | 2017-02-14 | — | — | US | disclosed |
| US-9567297-B2 | Method for synthesizing of thioesters by using compound as catalyst | NATIONAL CENTRAL UNIVERSITY (TW) | 2017-02-14 | — | — | US | disclosed |
| US-9567297-B2 | Method for synthesizing of thioesters by using compound as catalyst | NATIONAL CENTRAL UNIVERSITY (TW) | 2017-02-14 | — | — | US | disclosed |
| US-20160340303-A1 | Method for Synthesizing of Thioesters by Using Compound as Catalyst | NATIONAL CENTRAL UNIVERSITY | 2016-11-24 | — | — | US | disclosed |
| US-20160340303-A1 | Method for Synthesizing of Thioesters by Using Compound as Catalyst | NATIONAL CENTRAL UNIVERSITY | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340303-A1 | Method for Synthesizing of Thioesters by Using Compound as Catalyst | ACOT7, TST, STS | KMT2A 1756/4885CES2 164/4885CES1 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.