SCHEMBL1824401

SCHEMBL1824401

CC(=O)OSSOC(=O)CN1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 1/20 0.36
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 3/20 0.34
KDM4E B2RXH2 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
G6PD P11413 1/20 0.34
HTT P42858 1/20 0.34
GFER P55789 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX12 P18054 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1027065 0.77 ALDH1A1 (0.37) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL2754581 0.74 ALDH1A1 (0.49) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL4671579 0.73 ALDH1A1 (0.39) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL2242400 0.73 SMN1; SMN2 (0.38) ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL7796008 0.71 RAB9A (0.41) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL5091798 0.71 TSHR (0.44) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL18825277 0.71 GSK3A (0.61) ALDH1A1RAB9AMEN1KMT2ALMNA
SCHEMBL2002948 0.70 ALDH1A1 (0.42) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL668458 0.70 RAB9A (0.40) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL22147439 0.69 ALDH1A1 (0.49) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867300-A2 Intracorporeal occlusive device Sethel Interventional, Inc. (US) 2007-12-19 EP claimed
EP-1200012-A2 INTRACORPOREAL OCCLUSIVE DEVICE Sethel Interventional, Inc. (US) 2002-05-02 EP claimed
WO-2000072781-A2 INTRACORPOREAL OCCLUSIVE DEVICE SETHEL INTERVENTIONAL, INC. (US) 2000-12-07 WO claimed
US-20240042194-A1 Methods of Implanting a Device into a Brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-02-08 US disclosed
US-11648394-B2 Methods of implanting a device into a brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-05-16 US disclosed
US-20210361935-A1 Methods of Implanting a Device into a Brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-11-25 US disclosed
US-9788840-B2 Intracorporeal occlusive device and method Marks, Michael P. (US) 2017-10-17 US disclosed
US-9526505-B2 Intracorporeal occlusive device and method MICROVENTION, INC. (US) 2016-12-27 US disclosed
EP-1992308-B1 Intracorporeal occlusive device MICROTRANSFORM INC (US) 2015-10-28 EP disclosed
US-20150173771-A1 Intracorporeal Occlusive Device And Method MARKS, MICHAEL P. 2015-06-25 US disclosed
US-8932317-B2 Intracorporeal occlusive device and method MICROVENTION, INC. (US) 2015-01-13 US disclosed
WO-2002043616-A2 STENT DEVICES WITH DETACHABLE DISTAL OR PROXIMAL WIRES SCIMED LIFE SYSTEMS, INC. (US) 2002-06-06 WO disclosed
EP-1200012-A2 INTRACORPOREAL OCCLUSIVE DEVICE Sethel Interventional, Inc. (US) 2002-05-02 EP disclosed
US-20020040235-A1 Endovascular apparatus HOLMAN THOMAS J (US) 2002-04-04 US disclosed
US-6319276-B1 Endovascular apparatus SCIMED LIFE SYSTEMS, INC. 2001-11-20 US disclosed
WO-2000072781-A2 INTRACORPOREAL OCCLUSIVE DEVICE SETHEL INTERVENTIONAL, INC. (US) 2000-12-07 WO disclosed
US-6059823-A Endovascular apparatus SCIMED LIFE SYSTEMS, INC. (US) 2000-05-09 US disclosed
EP-0959810-A1 ENDOVASCULAR APPARATUS SciMed Life Systems, Inc. (US) 1999-12-01 EP disclosed
US-5871537-A Endovascular apparatus SCIMED LIFE SYSTEMS, INC. (US) 1999-02-16 US disclosed
WO-1997029716-A1 ENDOVASCULAR APPARATUS SCIMED LIFE SYSTEMS, INC. (US) 1997-08-21 WO disclosed