Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258841 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL2754581 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL3254635 | 0.77 | RAB9A (0.37) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL7796008 | 0.75 | RAB9A (0.41) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL5091798 | 0.74 | TSHR (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL18825277 | 0.74 | GSK3A (0.61) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL28014499 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL668458 | 0.74 | RAB9A (0.40) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL2002948 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL9532098 | 0.73 | PLA2G10 (0.40) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267877-A1 | Peptide-based carrier devices for stellate cells | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-10-30 | — | — | US | disclosed |
| US-7348313-B2 | Method for targeting cells involved in sclerotic and/or fibrotic diseases | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-03-25 | — | — | US | disclosed |
| EP-1117443-B1 | PEPTIDE-BASED CARRIER DEVICES FOR STELLATE CELLS | STICHTING TECH WETENSCHAPP (NL) | 2005-11-02 | — | — | EP | disclosed |
| US-20050227916-A1 | Peptide stellate carrier devices for stellate cells | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2005-10-13 | — | — | US | disclosed |
| US-6844319-B1 | Peptide-based carrier devices for stellate cells | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2005-01-18 | — | — | US | disclosed |
| EP-1117443-A1 | PEPTIDE-BASED CARRIER DEVICES FOR STELLATE CELLS | Stichting voor de Technische Wetenschappen (NL) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000023113-A1 | PEPTIDE-BASED CARRIER DEVICES FOR STELLATE CELLS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2000-04-27 | — | — | WO | disclosed |