Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796008 | 0.80 | RAB9A (0.41) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL2754581 | 0.78 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL2002948 | 0.78 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL13895524 | 0.77 | RAB9A (0.39) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL18825277 | 0.75 | GSK3A (0.61) | RAB9AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4671579 | 0.74 | ALDH1A1 (0.39) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL22147439 | 0.74 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL3254635 | 0.74 | RAB9A (0.37) | RAB9ASMN1; SMN2ALDH1A1ALOX12HPGD | |
| SCHEMBL9532098 | 0.74 | PLA2G10 (0.40) | RAB9ASMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL236431 | 0.72 | TSHR (0.56) | RAB9ASMN1; SMN2ALDH1A1ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2272865-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2017287-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2009-01-21 | — | — | EP | disclosed |
| EP-1398327-B1 | Method of producing hydroxyalkyl starch derivatives | FRESENIUS KABI DE GMBH (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-20050238723-A1 | Method of producing hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| WO-2004024776-A1 | METHOD OF PRODUCING HYDROXYALKYL STARCH DERIVATIVES | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2004-03-25 | — | — | WO | disclosed |
| EP-1398327-A1 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | RAB9A 3723/4885SMN1; SMN2 4623/4885ALDH1A1 304/4885 |
| US-20050238723-A1 | Method of producing hydroxyalkyl starch derivatives | HACL2, HAAO, LIPA | RAB9A 3723/4885SMN1; SMN2 4623/4885ALDH1A1 304/4885 |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | RAB9A 3723/4885SMN1; SMN2 4623/4885ALDH1A1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.