SCHEMBL18248047

SCHEMBL18248047

CN[C@@H](CC(C)(C)C)C(=O)OC(C)C(=O)OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 5/20 0.50
▸ CTSB P07858 4/20 0.50
▸ CTSL P07711 3/20 0.50
▸ CTSK P43235 7/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ PPARA Q07869 1/20 0.40
▸ S1PR4 O95977 1/20 0.40
▸ S1PR1 P21453 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18256500 1.00 CTSS (0.50) CTSSCTSBCTSLCTSKALDH1A1
Hydrochloric Acid SCHEMBL31560870 0.99 CTSS (0.49) CTSSCTSBCTSLCTSKALDH1A1
Hydrochloric Acid SCHEMBL23269876 0.99 CTSS (0.49) CTSSCTSBCTSLCTSKALDH1A1
SCHEMBL18256483 0.91 CTSS (0.42) CTSSCTSBCTSLCTSKALDH1A1
SCHEMBL22502762 0.89 CTSL (0.39) CTSSCTSBCTSLCTSKALDH1A1
SCHEMBL22651659 0.88 PPARA (0.41) CTSSCTSBCTSLCTSKALDH1A1
SCHEMBL18256327 0.87 CTSK (0.53) CTSSCTSBCTSLCTSKS1PR4
SCHEMBL23269880 0.87 CTSK (0.53) CTSSCTSBCTSLCTSKS1PR4
SCHEMBL18248005 0.87 CTSK (0.53) CTSSCTSBCTSLCTSKS1PR4
SCHEMBL19088457 0.87 CTSK (0.53) CTSSCTSBCTSLCTSKS1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286455-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2025-04-29 — — US disclosed
EP-3922639-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2021-12-15 — — EP disclosed
EP-3298027-B1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2021-04-28 — — EP disclosed
US-20200354408-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2020-11-12 — — US disclosed
US-10793604-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2020-10-06 — — US disclosed
US-20180362589-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL INC. (US) 2018-12-20 — — US disclosed
US-10081656-B2 Anthelmintic depsipeptide compounds MERIAL, INC. (US) 2018-09-25 — — US disclosed
EP-3298027-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Merial, Inc. (US) 2018-03-28 — — EP disclosed
US-20170022253-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL INC. (US) 2017-01-26 — — US disclosed
WO-2016187534-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2016-11-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170022253-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885
US-20180362589-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885
US-10793604-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885
US-10081656-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885
US-20200354408-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885
US-12286455-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSS 245/4885CTSB 101/4885CTSL 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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