SCHEMBL18256327

SCHEMBL18256327

CN[C@@H](CC(C)C)C(=O)O[C@H](C)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 11/20 0.53
▸ CTSS P25774 4/20 0.50
▸ CTSL P07711 3/20 0.50
▸ CTSB P07858 3/20 0.50
▸ S1PR4 O95977 1/20 0.48
▸ S1PR1 P21453 1/20 0.48
▸ CAPN1 P07384 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23269880 1.00 CTSK (0.53) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL18248005 1.00 CTSK (0.53) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL19088457 1.00 CTSK (0.53) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL27726507 0.90 CTSK (0.59) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL7374655 0.90 CTSK (0.59) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL29398302 0.90 CTSK (0.59) CTSKCTSSCTSLCTSBS1PR4
Hydrochloric Acid SCHEMBL27747285 0.89 CTSK (0.58) CTSKCTSSCTSLCTSBS1PR4
Hydrochloric Acid SCHEMBL27747283 0.89 CTSK (0.58) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL21266672 0.88 CTSK (0.43) CTSKCTSSCTSLCTSBS1PR4
SCHEMBL18248047 0.87 CTSS (0.50) CTSKCTSSCTSLCTSBS1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676265-B1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-20 — — EP disclosed
US-12286455-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2025-04-29 — — US disclosed
US-20250019360-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES ELANCO ANIMAL HEALTH GMBH (DE) 2025-01-16 — — US disclosed
US-12122759-B2 Method for the synthesis of cyclic depsipeptides ELANCO ANIMAL HEALTH GMBH (DE) 2024-10-22 — — US disclosed
US-12018048-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2024-06-25 — — US disclosed
US-12018048-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2024-06-25 — — US disclosed
US-12018048-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2024-06-25 — — US disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 — — US disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 — — US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 — — US disclosed
US-10793604-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2020-10-06 — — US disclosed
EP-3676265-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES Bayer Animal Health GmbH (DE) 2020-07-08 — — EP disclosed
WO-2019217449-A1 ENDOPARASITIC DEPSIPEPTIDES ZOETIS SERVICES LLC (US) 2019-11-14 — — WO disclosed
US-20190248840-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2019-08-15 — — US disclosed
US-10344056-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2019-07-09 — — US disclosed
US-20170233438-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL INC. (US) 2017-08-17 — — US disclosed
US-20170233438-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL INC. (US) 2017-08-17 — — US disclosed
WO-2017116702-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2017-07-06 — — WO disclosed
US-20170022253-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL INC. (US) 2017-01-26 — — US disclosed
WO-2016187534-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2016-11-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10344056-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSK 185/4885CTSS 264/4885CTSL 129/4885
US-12018048-B2 Anthelmintic depsipeptide compounds VIP, DNPEP, DPEP1 CTSK 111/4885CTSS 156/4885CTSL 77/4885
US-20170022253-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSK 204/4885CTSS 245/4885CTSL 86/4885
US-11786575-B2 Endoparasitic depsipeptides VIP, PREP, NGLY1 CTSK 518/4885CTSS 145/4885CTSL 75/4885
US-20170233438-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSK 185/4885CTSS 264/4885CTSL 129/4885
US-12122759-B2 Method for the synthesis of cyclic depsipeptides DNPEP, NPEPPS, PREP CTSK 669/4885CTSS 1185/4885CTSL 799/4885
US-20250019360-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES DNPEP, NPEPPS, PREP CTSK 669/4885CTSS 1185/4885CTSL 799/4885
US-10793604-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSK 204/4885CTSS 245/4885CTSL 86/4885
US-11771738-B2 Endoparasitic depsipeptides VIP, PREP, VIPR1 CTSK 537/4885CTSS 155/4885CTSL 64/4885
US-20190248840-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP CTSK 185/4885CTSS 264/4885CTSL 129/4885
US-12286455-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP CTSK 204/4885CTSS 245/4885CTSL 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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