Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.61 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.58 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.56 |
| ▸ | UGCG | Q16739 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508674 | 0.88 | MEN1 (0.48) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL18037181 | 0.82 | GAA (0.50) | ASAH1ALDH1A1ACER2SMPD2SMPD1 | |
| SCHEMBL8689297 | 0.82 | LMNA (0.49) | MEN1KMT2AMAPT | |
| SCHEMBL9763082 | 0.81 | ASAH1 (0.69) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL5599045 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL4183115 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL4139311 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL4139305 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL9472620 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL16714723 | 0.80 | ALDH1A1 (0.72) | ASAH1ALDH1A1ACER2CERT1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297621-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | Dublin City University (IE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016185025-A1 | A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE | DUBLIN CITY UNIVERSITY (IE) | 2016-11-24 | — | — | WO | disclosed |