Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508674 | 0.87 | MEN1 (0.48) | MEN1KMT2ACTSLCTSSCTSK | |
| SCHEMBL16891544 | 0.83 | GAA (0.50) | KMT2AMAPT | |
| SCHEMBL18248611 | 0.82 | ASAH1 (0.61) | MEN1KMT2AMAPT | |
| SCHEMBL17777055 | 0.81 | TACR3 (0.47) | LMNAMEN1KMT2ACTSLCTSS | |
| SCHEMBL250886 | 0.80 | TACR3 (0.49) | LMNAMEN1KMT2ACTSLCTSS | |
| SCHEMBL16989172 | 0.80 | TACR3 (0.49) | LMNAMEN1KMT2ACTSLCTSS | |
| SCHEMBL16989173 | 0.80 | TACR3 (0.49) | LMNAMEN1KMT2ACTSLCTSS | |
| SCHEMBL18037181 | 0.78 | GAA (0.50) | LMNAMEN1KMT2APRCPTSHR | |
| SCHEMBL11256205 | 0.78 | HTT (0.53) | LMNAMEN1KMT2ACTSLCTSS | |
| SCHEMBL15526167 | 0.78 | ALDH1A1 (0.54) | LMNAPRCPMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792760-A | USEFUL IN TREATMENT OF PSYCHOLOGICAL AND CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |