Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249490 | 0.84 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3FAAH | |
| SCHEMBL18249445 | 0.76 | UTS2R (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL995722 | 0.75 | LMNA (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 | |
| SCHEMBL23788250 | 0.75 | ALDH1A1 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL24439478 | 0.74 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL9357923 | 0.74 | ALDH1A1 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL7028935 | 0.73 | CYP1A2 (0.48) | FAAHTSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL28084282 | 0.73 | TSHR (0.54) | FAAHTSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL28084284 | 0.73 | TSHR (0.54) | FAAHTSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL10292049 | 0.73 | ALDH1A1 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |