Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249392 | 0.84 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4FAAH | |
| SCHEMBL31426915 | 0.74 | FAAH (0.51) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL24439478 | 0.74 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| SCHEMBL18249489 | 0.74 | MMP1 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4MMP1 | |
| SCHEMBL20164268 | 0.74 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18249445 | 0.73 | UTS2R (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28158241 | 0.73 | FAAH (0.58) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL995722 | 0.72 | LMNA (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4CA12 | |
| SCHEMBL18856239 | 0.72 | FAAH (0.61) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18249406 | 0.71 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016184884-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-24 | — | — | WO | disclosed |