Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100685 | 0.87 | ALKBH5 (0.64) | ALKBH5FTOADORA3ADORA2AMEN1 | |
| SCHEMBL25564874 | 0.80 | ADORA3 (0.49) | ALKBH5FTOADORA3ADORA2AKDM4E | |
| SCHEMBL19271312 | 0.80 | KDM5A (0.45) | ALKBH5FTOROCK2DYRK1AMAOA | |
| SCHEMBL24311758 | 0.80 | KDM4E (0.53) | ALKBH5FTOKDM4EMAPTROCK2 | |
| SCHEMBL18415773 | 0.78 | ALKBH5 (0.45) | ALKBH5FTOMEN1NPC1HCRTR1 | |
| SCHEMBL146377 | 0.78 | ALKBH5 (1.00) | ALKBH5FTOMEN1NPC1HCRTR1 | |
| SCHEMBL1609661 | 0.78 | ADORA3 (0.54) | ADORA3ADORA2ATOP2AROCK2NFATC1 | |
| SCHEMBL25703709 | 0.78 | IDO1 (0.41) | ALKBH5FTOADORA3ADORA2ANPC1 | |
| SCHEMBL29358773 | 0.77 | GPR3 (0.64) | ALKBH5FTOADORA3ADORA2AMEN1 | |
| SCHEMBL280032 | 0.77 | GPR3 (0.64) | ALKBH5FTOADORA3ADORA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160343957-A1 | ELECTRON TRANSPORT MATERIALS FOR ELECTRONIC APPLICATIONS | LG CHEM, LTD. (KR) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160343957-A1 | ELECTRON TRANSPORT MATERIALS FOR ELECTRONIC APPLICATIONS | CCNE2, ESR2, CCNL2 | ALKBH5 3585/4885FTO 2481/4885ADORA3 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.