Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253293 | 0.87 | ALKBH5 (0.64) | ALKBH5FTOTOP2AKDM4EMAPT | |
| SCHEMBL25564871 | 0.80 | TOP2A (0.42) | ALKBH5FTOTOP2AKDM4EMAPT | |
| SCHEMBL19271296 | 0.80 | MAOA (0.48) | ALKBH5FTOMAOAMAOBACHE | |
| SCHEMBL18415760 | 0.78 | CYP17A1 (0.45) | ALKBH5FTOKDM4EMAOAMAOB | |
| SCHEMBL146377 | 0.78 | ALKBH5 (1.00) | ALKBH5FTOKDM4EMAPTACHE | |
| SCHEMBL280029 | 0.78 | TOP2A (0.50) | TOP2AMAPTMAOAMAOBACHE | |
| SCHEMBL25703708 | 0.78 | TOP2A (0.47) | ALKBH5FTOTOP2AKDM4EMAPT | |
| SCHEMBL21168173 | 0.77 | ALKBH5 (0.55) | ALKBH5FTOTOP2AKDM4EMAPT | |
| SCHEMBL29548306 | 0.77 | GPR3 (0.64) | ALKBH5FTOTOP2AKDM4EMAPT | |
| SCHEMBL280028 | 0.77 | GPR3 (0.64) | ALKBH5FTOTOP2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160343957-A1 | ELECTRON TRANSPORT MATERIALS FOR ELECTRONIC APPLICATIONS | LG CHEM, LTD. (KR) | 2016-11-24 | — | — | US | disclosed |
| US-20100256379-A1 | ANTI-VIRAL AGENT CONTAINING HETEROCYCLIC AROMATIC COMPOUND AS ACTIVE INGREDIENT | KAGOSHIMA UNIVERSITY | 2010-10-07 | — | — | US | disclosed |
| US-20100256379-A1 | ANTI-VIRAL AGENT CONTAINING HETEROCYCLIC AROMATIC COMPOUND AS ACTIVE INGREDIENT | KAGOSHIMA UNIVERSITY | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160343957-A1 | ELECTRON TRANSPORT MATERIALS FOR ELECTRONIC APPLICATIONS | CCNE2, ESR2, CCNL2 | ALKBH5 3585/4885FTO 2481/4885TOP2A 2767/4885 |
| US-20100256379-A1 | ANTI-VIRAL AGENT CONTAINING HETEROCYCLIC AROMATIC COMPOUND AS ACTIVE INGREDIENT | H1-10, MAVS, HNRNPH3 | ALKBH5 950/4885FTO 3329/4885TOP2A 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.