Sugi Predict

Sugi Predict / Compounds / Methoxymethane

Methoxymethane

Methoxymethane

SCHEMBL1825482

CC(OOS(=O)(=O)c1ccccc1)c1ccccc1.COC

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 1/20 0.36
▸ HCAR2 Q8TDS4 1/20 0.36
▸ TDP1 Q9NUW8 2/20 0.35
▸ HTR6 P50406 2/20 0.35
▸ PARL Q9H300 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ MAPT P10636 4/20 0.34
▸ LMNA P02545 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ PSIP1 O75475 1/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ HPGD P15428 1/20 0.34
▸ HSP90AA1 P07900 2/20 0.34
▸ MAPK1 P28482 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.34
▸ PAX8 Q06710 1/20 0.34
▸ MPI P34949 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1825460 0.96 CCR5 (0.38) CCR5HCAR2TDP1HTR6PARL
SCHEMBL1825974 0.85 TSHR (0.43) CCR5ALDH1A1HPGDRAB9ASMN1; SMN2
Methoxymethane SCHEMBL1825485 0.83 MAPT (0.36) TDP1HTR6PARLALDH1A1MAPT
SCHEMBL30930716 0.80 HTR6 (0.41) TDP1HTR6PARLALDH1A1MAPT
SCHEMBL1827608 0.79 TSHR (0.36) TDP1HTR6PARLALDH1A1MAPT
Methoxymethane SCHEMBL1824463 0.79 HTR6 (0.36) TDP1HTR6PARLALDH1A1MAPT
SCHEMBL2476595 0.78 HCAR2 (0.40) HCAR2TDP1HTR6PARLALDH1A1
Methoxymethane SCHEMBL1825502 0.78 CYP1A2 (0.33) TDP1HTR6PARLALDH1A1MAPT
SCHEMBL11857545 0.77 ALDH1A1 (0.43) HCAR2TDP1ALDH1A1MAPTLMNA
SCHEMBL1826870 0.75 ALDH1A1 (0.37) CCR5TDP1HTR6PARLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2161254-B1 Intermediate for preparing a biaryl compound SUMITOMO CHEMICAL CO (JP) 2014-08-13 — — EP disclosed
EP-1481967-B1 PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2011-05-04 — — EP disclosed
US-7714157-B2 Process for preparing a biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-05-11 — — US disclosed
EP-2161254-A1 Intermediate for preparing a biaryl compound Sumitomo Chemical Company, Limited (JP) 2010-03-10 — — EP disclosed
US-20070270603-A1 Process for preparing a biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED 2007-11-22 — — US disclosed
US-7271280-B2 Process for preparing a biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-09-18 — — US disclosed
EP-1481967-A1 PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2004-12-01 — — EP disclosed
US-20040158093-A1 Process for preparing a biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158093-A1 Process for preparing a biaryl compound CYP1B1, REL, CYP2F1 CCR5 1203/4885HCAR2 1960/4885TDP1 4543/4885
US-20070270603-A1 Process for preparing a biaryl compound CYP4A11, CYP4B1, CYP51A1 CCR5 3598/4885HCAR2 2103/4885TDP1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.