Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765702 | 0.85 | OPRM1 (0.53) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL18256186 | 0.82 | CYP3A4 (0.43) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL25703446 | 0.79 | ALDH1A1 (0.53) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL15998890 | 0.79 | OPRM1 (0.51) | OPRM1ALDH1A1OPRL1CHRNB2CHRNA3 | |
| SCHEMBL16589307 | 0.79 | OPRM1 (0.43) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL18253214 | 0.79 | BTK (0.36) | ALDH1A1CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL617485 | 0.78 | OPRM1 (0.51) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL21765703 | 0.78 | OPRM1 (0.47) | OPRM1ALDH1A1CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL21303477 | 0.78 | BTK (0.39) | ALDH1A1CYP2D6CYP2C9CYP1A2HRH3 | |
| SCHEMBL16074977 | 0.78 | BTK (0.39) | ALDH1A1CYP2D6CYP2C9CYP1A2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340339-A1 | PYRAZOLE COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340339-A1 | PYRAZOLE COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LYN | OPRM1 4783/4885ALDH1A1 3342/4885CYP2D6 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.