Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765702 | 0.92 | OPRM1 (0.53) | OPRM1ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL15998890 | 0.86 | OPRM1 (0.51) | OPRM1ALDH1A1OPRL1USP2 | |
| SCHEMBL25703446 | 0.86 | ALDH1A1 (0.53) | OPRM1ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL617485 | 0.85 | OPRM1 (0.51) | OPRM1ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL15998880 | 0.84 | OPRM1 (0.46) | OPRM1ALDH1A1CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL13131126 | 0.83 | HSD11B1 (0.51) | OPRM1ALDH1A1CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL22030233 | 0.81 | ALDH1A1 (0.42) | OPRM1ALDH1A1MAPK1CYP2C19CYP2D6 | |
| SCHEMBL26854735 | 0.80 | OPRM1 (0.46) | OPRM1ALDH1A1TSHROPRL1HSD17B10 | |
| SCHEMBL22802557 | 0.80 | ALDH1A1 (0.59) | OPRM1ALDH1A1OPRL1 | |
| SCHEMBL26832959 | 0.80 | ALDH1A1 (0.49) | OPRM1ALDH1A1MAPK1CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |