Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25703446 | 0.94 | ALDH1A1 (0.53) | OPRM1ALDH1A1OPRL1CHRNB2CHRNA3 | |
| SCHEMBL15998890 | 0.94 | OPRM1 (0.51) | OPRM1ALDH1A1OPRL1HSD11B1CHRNB2 | |
| SCHEMBL21765703 | 0.92 | OPRM1 (0.47) | OPRM1ALDH1A1OPRL1CYP2D6CYP2C19 | |
| SCHEMBL617485 | 0.92 | OPRM1 (0.51) | OPRM1ALDH1A1OPRL1HSD11B1CYP2D6 | |
| SCHEMBL15998880 | 0.91 | OPRM1 (0.46) | OPRM1ALDH1A1OPRL1HSD11B1CYP2D6 | |
| SCHEMBL13131126 | 0.90 | HSD11B1 (0.51) | OPRM1ALDH1A1OPRL1HSD11B1CYP2D6 | |
| SCHEMBL26854735 | 0.87 | OPRM1 (0.46) | OPRM1ALDH1A1OPRL1HSD11B1CHRNB2 | |
| SCHEMBL22802557 | 0.86 | ALDH1A1 (0.59) | OPRM1ALDH1A1OPRL1CHRNB2CHRNA3 | |
| SCHEMBL16589307 | 0.86 | OPRM1 (0.43) | OPRM1ALDH1A1OPRL1CYP2D6CYP2C19 | |
| SCHEMBL25876408 | 0.86 | ALDH1A1 (0.50) | OPRM1ALDH1A1CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |