Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500856 | 0.83 | FAAH (0.62) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL20174142 | 0.82 | MEN1 (0.71) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL22188060 | 0.81 | FAAH (0.55) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL4758347 | 0.80 | FAAH (0.68) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL9618659 | 0.79 | FAAH (0.81) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL20163294 | 0.79 | FAAH (0.72) | FAAHEPHX2CASP2SLC6A5NAAA | |
| SCHEMBL20998615 | 0.79 | PAOX (0.50) | MEN1KMT2AEPHX2CASP2 | |
| SCHEMBL31631415 | 0.79 | FAAH (0.61) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL6683810 | 0.78 | FAAH (0.72) | FAAHMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL29637710 | 0.78 | FAAH (0.72) | FAAHMEN1KMT2AEPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016184561-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-11-24 | — | — | WO | disclosed |