SCHEMBL18256434

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23279491	1.00	AAK1 (0.37)	AAK1MMP13CA14CA12PIK3CD
	SCHEMBL24297646	0.89	AAK1 (0.37)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL18248195	0.86	AAK1 (0.36)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL18248194	0.86	AAK1 (0.36)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL30916076	0.86	AAK1 (0.36)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL21447817	0.84	AAK1 (0.35)	AAK1MMP13CA14CA12PIK3CD
	SCHEMBL3301368	0.83	AAK1 (0.38)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL20586574	0.83	MMP13 (0.38)	AAK1MMP13HDAC1HDAC2HDAC6
	SCHEMBL18235375	0.83	AAK1 (0.38)	AAK1MMP13CA14CA12DGAT1
	SCHEMBL18248156	0.83	MMP13 (0.38)	AAK1MMP13HDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.