Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.56 |
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257555 | 1.00 | CTSD (0.56) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL18257544 | 0.91 | CTSD (0.57) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL18257575 | 0.91 | CTSD (0.57) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL23616314 | 0.91 | CTSD (0.56) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL18257547 | 0.91 | CTSD (0.56) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL7137259 | 0.88 | CTSD (0.57) | CTSDRENCTSSCTSKCTSB | |
| SCHEMBL21367520 | 0.88 | CTSS (0.58) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL21367482 | 0.87 | REN (0.60) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL18257539 | 0.87 | REN (0.60) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL20825306 | 0.87 | REN (0.60) | RENCTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |