Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDH1 | P12830 | 1/20 | 0.70 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.70 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892967 | 0.91 | CDH1 (0.82) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL20149361 | 0.82 | CDH1 (1.00) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL892878 | 0.78 | ALDH1A1 (0.72) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL16401825 | 0.78 | CDH1 (0.63) | CDH1CTNNB1TCF7L2ALDH1A1MAPT | |
| SCHEMBL11275129 | 0.76 | CDH1 (0.61) | CDH1CTNNB1TCF7L2ALDH1A1MAPT | |
| SCHEMBL72786 | 0.76 | ALDH1A1 (1.00) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL71299 | 0.76 | ALDH1A1 (1.00) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL11902059 | 0.75 | CDH1 (0.59) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL1178695 | 0.74 | ALDH1A1 (0.72) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 | |
| SCHEMBL72428 | 0.74 | ALDH1A1 (0.72) | CDH1CTNNB1TCF7L2ALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187050-A1 | METHODS AND COMPOSITIONS OF SUBSTITUTED 5H-[1,2,5]OXADIAZOLO[3',4':5,6] PYRAZIONO[2,3-B]INDOLE ANALOGS AS INHIBITORS OF BETA-CATENIN/T-CELL FACTOR PROTEIN-PROTEIN INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-11-24 | — | — | WO | disclosed |