Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDH1 | P12830 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.61 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ACR | P10323 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892967 | 0.84 | CDH1 (0.82) | CDH1CTNNB1TCF7L2NPC1RAB9A | |
| SCHEMBL16401825 | 0.84 | CDH1 (0.63) | CDH1CTNNB1TCF7L2NPC1RAB9A | |
| SCHEMBL2791692 | 0.83 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2TP53ACR | |
| SCHEMBL2678323 | 0.82 | ALDH1A1 (0.73) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24198778 | 0.79 | SMN1; SMN2 (0.59) | CDH1CTNNB1TCF7L2NPC1RAB9A | |
| SCHEMBL5375870 | 0.79 | ACR (0.58) | NPC1RAB9ASMN1; SMN2TP53ACR | |
| SCHEMBL20149361 | 0.76 | CDH1 (1.00) | CDH1CTNNB1TCF7L2NPC1RAB9A | |
| SCHEMBL18257901 | 0.76 | CDH1 (0.70) | CDH1CTNNB1TCF7L2NPC1RAB9A | |
| SCHEMBL9057987 | 0.75 | TP53 (0.65) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL1686347 | 0.75 | POLB (0.66) | CDH1CTNNB1TCF7L2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0048162-A1 | Isoxazolylbenzamides | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |