Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MB | P02144 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588899 | 0.83 | ESR1 (0.42) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL27365059 | 0.81 | CYP3A4 (0.41) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9614627 | 0.80 | HSD17B3 (0.44) | ESR1ESR2ALDH1A1TSHRLMNA | |
| SCHEMBL10926482 | 0.79 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6909286 | 0.78 | CA2 (0.42) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL8390888 | 0.77 | NPC1 (0.51) | ESR1ESR2ALDH1A1CYP3A4ACHE | |
| SCHEMBL27872334 | 0.77 | ESR1 (0.40) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9645342 | 0.77 | ESR1 (0.40) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6801979 | 0.76 | LTB4R2 (0.53) | ESR1ESR2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL935744 | 0.76 | MLYCD (0.41) | ESR1ESR2ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097904-B1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | AFFICHEM (FR) | 2019-08-14 | — | — | EP | disclosed |
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |
| EP-3097904-A1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | Affichem (FR) | 2016-11-30 | — | — | EP | disclosed |