Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.31 |
| ▸ | GLRB | P48167 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648102 | 0.84 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11654877 | 0.81 | THRB (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11668060 | 0.81 | THRB (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11999077 | 0.79 | POLB (0.55) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL24708610 | 0.79 | POLB (0.55) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3372532 | 0.77 | PPARA (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL23638613 | 0.77 | CA2 (0.43) | POLBHTTTSHRCA1CA2 | |
| SCHEMBL7627033 | 0.77 | TDP1 (0.40) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL19252768 | 0.77 | TDP1 (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL7627057 | 0.77 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2856218-B9 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB (US) | 2016-11-30 | — | — | EP | disclosed |