SCHEMBL18268917

SCHEMBL18268917

CC1(C)CCCC(=O)OC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C9 P11712 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18268916 0.93 CA1 (0.44) CA1CA9LMNAALDH1A1TP53
SCHEMBL3444289 0.88 CA1 (0.56) CA1CA9LMNAALDH1A1TP53
SCHEMBL360166 0.86 CA1 (0.50) CA1CA9LMNAALDH1A1TP53
SCHEMBL758910 0.86
SCHEMBL11824753 0.85 CA1 (0.57) CA1CA9LMNAALDH1A1TP53
SCHEMBL530556 0.85 CA1 (0.57) CA1CA9LMNAALDH1A1TP53
SCHEMBL11536217 0.84 CA1 (0.48) CA1CA9LMNAALDH1A1TP53
SCHEMBL31743255 0.84 CA1 (0.48) CA1CA9LMNAALDH1A1TP53
SCHEMBL9265626 0.84 CA1 (0.48) CA1CA9LMNAALDH1A1TP53
Ethylene SCHEMBL29492957 0.82 CA1 (0.46) CA1CA9LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653598-A1 PROCESSES AND INTERMEDIATES FOR PREPARING , -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS Gemphire Therapeutics Inc. (US) 2020-05-20 EP disclosed
US-9951163-B2 (Meth)acrylate compound, (meth)acrylic copolymer and photosensitive resin composition containing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-04-24 US disclosed
US-20170158601-A9 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2017-06-08 US disclosed
US-20160347896-A1 (METH)ACRYLATE COMPOUND, (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-12-01 US disclosed
US-20160347896-A1 (METH)ACRYLATE COMPOUND, (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158601-A9 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS BCKDK, DGKI, DDC CA1 212/4885CA9 347/4885LMNA 1100/4885
US-20160347896-A1 (METH)ACRYLATE COMPOUND, (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME REV1, EEF1A1, EEF1A2 CA1 4153/4885CA9 3587/4885LMNA 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.