SCHEMBL182716

SCHEMBL182716

COc1c[c]ccc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316773 0.82
SCHEMBL8674 0.78 CA2 (0.46)
SCHEMBL972325 0.77 ALDH1A1 (0.43)
SCHEMBL17203718 0.77 IRAK4 (0.34)
SCHEMBL27494520 0.76 CA2 (0.43)
SCHEMBL28251730 0.76 CA2 (0.43)
SCHEMBL6541679 0.76 CA1 (0.38)
SCHEMBL2138768 0.76 CA2 (0.43)
SCHEMBL96297 0.76
SCHEMBL19924944 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1906 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369011-B New green method for preparing 2-diaryl methyl substituted-1-naphthol compound 湖南理工学院 2024-07-09 CN claimed
EP-4376864-A1 THERAPEUTIC FORMULATIONS FROM PELARGONIUM SP. AND METHOD OF USE IN RESPIRATORY VIRAL INFECTIONS Subhadra, Bobban (US) 2024-06-05 EP claimed
CN-117466771-A Green preparation method of alpha-aminonitrile 山东达因海洋生物制药股份有限公司 2024-01-30 CN claimed
CN-115368218-B Method for preparing 4-diaryl methyl substituted phenol compound 湖南理工学院 2024-01-02 CN claimed
CN-114315610-B Novel method for preparing 4-dimethyl aryl substituted aniline compound by silver catalysis 湖南理工学院 2023-11-10 CN claimed
CN-116854601-A Novel method for preparing 4-diaryl methyl substituted aniline compound by mediation of hexafluoroisopropanol 湖南理工学院 2023-10-10 CN claimed
CN-116715591-A Novel method for preparing 2-diaryl methyl substituted aniline compound by mediation of hexafluoroisopropanol 湖南理工学院 2023-09-08 CN claimed
CN-116693404-A Novel method for preparing 4-diaryl methyl substituted tertiary aromatic amine compound by mediation of hexafluoroisopropanol 湖南理工学院 2023-09-05 CN claimed
CN-112679321-B New green method for preparing 1-diaryl methyl substituted-2-naphthol compound 湖南理工学院 2023-08-08 CN claimed
US-11712438-B2 Phenyl derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2023-08-01 US claimed
EP-0182279-A1 Process for the optical resolution of racemic mixtures of alpha-naphtyl-propionic acids ALFA WASSERMANN S.p.A. (IT) 1986-05-28 EP claimed
EP-0178919-A2 Aminophenol derivatives GLAXO GROUP LIMITED (GB) 1986-04-23 EP claimed
EP-0136266-A2 7-Beta-acylamido-3-cephem-4-carboxylic-acid esters, process for their preparation, pharmaceutical compositions and their application CIBA-GEIGY AG (CH) 1985-04-03 EP claimed
US-4469695-A 2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives AYERST, MCKENNA & HARRISON, INC. (CA) 1984-09-04 US claimed
US-4457935-A ANGIOTENSIN-CONVERTING ENZYME INHIBITOR SANTEN PHARMACEUTICAL CO., LTD. (JP) 1984-07-03 US claimed
US-4347371-A HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS SANTEN PHARMACEUTICAL CO., LTD. (JP) 1982-08-31 US claimed
EP-0004727-B1 BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-12 EP claimed
EP-0031104-A1 Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them SANTEN PHARMACEUTICAL CO., LTD. (JP) 1981-07-01 EP claimed
EP-0004727-A2 Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-17 EP claimed
US-3983160-A Process for the preparation of hydroxyphenylacetonitriles BAYER AKTIENGESELLSCHAFT (DT) 1976-09-28 US claimed