Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458021 | 0.85 | MAPT (0.40) | ALDH1A1MEN1KMT2AESR1KDM4E | |
| SCHEMBL3043536 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AESR1TOP2A | |
| SCHEMBL27944106 | 0.83 | ESR1 (0.43) | ESR1TSHRGAAGLA | |
| SCHEMBL127280 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL929861 | 0.80 | SMPD1 (0.47) | ALDH1A1MEN1KMT2AESR1HPGD | |
| SCHEMBL931517 | 0.80 | SMPD1 (0.47) | ALDH1A1MEN1KMT2AESR1HPGD | |
| SCHEMBL10458094 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AESR1KDM4E | |
| SCHEMBL19924945 | 0.78 | IDO1 (0.44) | ALDH1A1GAA | |
| SCHEMBL182716 | 0.77 | — | — | |
| SCHEMBL19925872 | 0.77 | ESR1 (0.44) | ALDH1A1ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651843-A | Bio-based toughening agent containing rigid-flexible structure and preparation method thereof | 福建师范大学 | 2021-11-16 | — | — | CN | claimed |
| CN-108358841-B | 4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivatives, and preparation method and application thereof | 厦门大学 | 2020-11-10 | — | — | CN | claimed |
| US-20190328690-A1 | METHODS FOR TREATING C-MET-DEPENDENT CANCERS | Board of Supervisors for the University of Louisiana System | 2019-10-31 | — | — | US | claimed |
| US-10329249-B1 | Sulindac derivatives | KING SAUD UNIVERSITY (SA) | 2019-06-25 | — | — | US | claimed |
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-07 | — | — | US | claimed |
| EP-3218458-B1 | IMPROVMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-01-02 | — | — | EP | claimed |
| US-10119097-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2018-11-06 | — | — | US | claimed |
| EP-3371151-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | Agency For Science, Technology And Research (SG) | 2018-09-12 | — | — | EP | claimed |
| US-20170298292-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2017-10-19 | — | — | US | claimed |
| EP-3218458-A1 | IMPROVMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2017-09-20 | — | — | EP | claimed |
| WO-2001021634-A1 | BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-03-29 | — | — | WO | claimed |
| EP-0740669-B1 | AZATRIOXASPIROALKENES AS PARASITICIDES | BAYER AG (DE) | 1999-04-28 | — | — | EP | claimed |
| EP-0740669-A1 | AZATRIOXASPIROALKENES AS PARASITICIDES | BAYER AG (DE) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019364-A1 | AZATRIOXASPIROALKENES AS PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | claimed |
| US-5321040-A | Pesticidal 1-aryl-5-(substituted N-cinnamylideneimino) pyrazoles | RHONE-POULENC INC. (US) | 1994-06-14 | — | — | US | claimed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
| EP-0511845-A1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1992-11-04 | — | — | EP | claimed |
| US-5147463-A | Organoleptic | BASF K&F CORPORATION (US) | 1992-09-15 | — | — | US | claimed |
| EP-0413162-A2 | Novel cyclic acetals | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1991-02-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | SMYD3, SMYD2, EHMT1 | ALDH1A1 373/4885MEN1 1006/4885KMT2A 29/4885 |
| US-10329249-B1 | Sulindac derivatives | SI, HRH2, SULT2A1 | ALDH1A1 10/4885MEN1 4866/4885KMT2A 3389/4885 |
| US-10119097-B2 | Organic compounds | OR10J3, CBR3, C9 | ALDH1A1 1321/4885MEN1 4212/4885KMT2A 3388/4885 |
| US-20190328690-A1 | METHODS FOR TREATING C-MET-DEPENDENT CANCERS | MET, VHL, MGMT | ALDH1A1 1056/4885MEN1 53/4885KMT2A 644/4885 |
| US-20170298292-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | OR10J3, C5, CBR3 | ALDH1A1 1512/4885MEN1 4172/4885KMT2A 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.