Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.44 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.42 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290456 | 1.00 | P2RX3 (0.45) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL18287233 | 0.91 | P2RX3 (0.42) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL18269541 | 0.91 | P2RX3 (0.42) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL18744141 | 0.83 | NT5E (0.51) | TGM2FUT5POLBKRASPNP | |
| SCHEMBL21078632 | 0.82 | P2RX3 (0.65) | P2RX3P2RX1P2RX4P2RY1RNASEL | |
| SCHEMBL21006550 | 0.81 | TGM2 (0.47) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL21007094 | 0.81 | TGM2 (0.46) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL21006295 | 0.80 | TGM2 (0.47) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL21007932 | 0.80 | TGM2 (0.45) | P2RX3P2RX1P2RX4P2RY1ENPP1 | |
| SCHEMBL21007856 | 0.79 | TGM2 (0.46) | P2RX3P2RX1P2RX4P2RY1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354490-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160354492-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160348099-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354492-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RX3 3314/4885P2RX1 3638/4885P2RX4 3935/4885 |
| US-20160348099-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RX3 3314/4885P2RX1 3638/4885P2RX4 3935/4885 |
| US-20160354490-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RX3 3314/4885P2RX1 3638/4885P2RX4 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.