Dimethylamine

Dimethylamine

SCHEMBL11221773

CCOc1cc(C)c(O)cc1C(C)C.CNC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 2/20 0.44
ADRA1A P35348 2/20 0.44
ADRA1B P35368 2/20 0.44
ACHE P22303 4/20 0.42
LMNA P02545 2/20 0.41
ESR1 P03372 1/20 0.40
PKM P14618 2/20 0.39
CYP1A2 P05177 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2D6 P10635 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
HTR2C P28335 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39
CHRNA4 P43681 1/20 0.39
HIF1A Q16665 1/20 0.39
GAA P10253 3/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28344355 0.95 ADRA1D (0.47) ADRA1DADRA1AADRA1BACHELMNA
Methylamine SCHEMBL11339729 0.92 ADRA1D (0.48) ADRA1DADRA1AADRA1BACHELMNA
SCHEMBL18272003 0.83 ADRA1D (0.50) ADRA1DADRA1AADRA1BACHELMNA
SCHEMBL8961537 0.83 ADRA1D (0.47) ADRA1DADRA1AADRA1BACHELMNA
Hydrochloric Acid SCHEMBL8924875 0.81 ADRA1D (0.46) ADRA1DADRA1AADRA1BACHELMNA
SCHEMBL16748338 0.81 ADRA1A (0.48) ADRA1DADRA1AADRA1BACHELMNA
SCHEMBL10706857 0.81 ADRA1D (0.48) ADRA1DADRA1AADRA1BACHELMNA
SCHEMBL2625747 0.80 LMNA (0.47) ADRA1DADRA1AADRA1BLMNAPKM
SCHEMBL10572211 0.80 KMT2A (0.47) LMNAGAAMAPT
SCHEMBL10570153 0.79 ADRA1D (0.41) ADRA1DADRA1AADRA1BACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57098243-A None JP disclosed
JP-S5798243-A PREPARATION OF 5-(N-METHYLAMINOETHOXY)CARVACROL FUJIREBIO INC 1982-06-18 JP disclosed