Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8924875 | 0.98 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BHTR1BMEN1 | |
| SCHEMBL10966124 | 0.94 | HTR1B (0.43) | ADRA1DADRA1AADRA1BHTR1BMEN1 | |
| SCHEMBL10706857 | 0.89 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| Dimethylamine SCHEMBL11221773 | 0.83 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL18272003 | 0.83 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL10671728 | 0.81 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL10641890 | 0.81 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL28344355 | 0.80 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BCYP1A2ADRA2A | |
| SCHEMBL8925940 | 0.80 | CYP1A2 (0.47) | ADRA1DADRA1AADRA1BHTR1BMEN1 | |
| SCHEMBL5207072 | 0.79 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062596-B1 | DERIVATIVES OF 4-AMINOETHOXY-5-ISOPROPYL-2-METHYL PHENOL, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | CORTIAL S.A. (FR) | 1985-07-03 | — | — | EP | claimed |
| JP-56100745-A | — | — | None | — | — | JP | disclosed |
| US-5561154-A | MUSCLE RELAXANTS | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOQUES APPLIQUEES IRCEBA (FR) | 1996-10-01 | — | — | US | disclosed |
| EP-0728479-A1 | Deacetyl moxisylyte in the treatment of acute urinary retention | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (IRCEBA) (FR) | 1996-08-28 | — | — | EP | disclosed |
| EP-0694300-A1 | Treatment of impotence | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (IRCEBA) (FR) | 1996-01-31 | — | — | EP | disclosed |
| US-5451609-A | DEACETLY MOXISYLYTE | INSTITUT DE RECHERCHES CHIMIQUES ET AL (FR) | 1995-09-19 | — | — | US | disclosed |
| US-4818772-A | ANTICOAGULANTS; CARDIOVASCULAR DISORDERS | SOCIETE CORTIAL S.A. (FR) | 1989-04-04 | — | — | US | disclosed |
| US-4721715-A | Derivatives of 4-(arylpiperazinyl-ethylaminoethoxy) phenol useful for effecting hypolipidemic therapy or cardiovascular therapy | SOCIETE CORTIAL, S.A. (FR) | 1988-01-26 | — | — | US | disclosed |
| JP-S56100745-A | 5- N-MONOALKYLAMINOETHOXY CARBACROL, ITS PREPARATION, AND DRUG COMPOSITION COMPRISING IT AS ACTIVE INGREDIENT | FUJIREBIO INC | 1981-08-12 | — | — | JP | disclosed |