SCHEMBL182907

SCHEMBL182907

CCCCCCCCC1COOc2c(c(C(=O)OCC)n(Cc3ccccc3)c2C(=O)OCC)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 4/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 2/20 0.36
TRPC5 Q9UL62 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 2/20 0.35
PRMT1 Q99873 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
MAOA P21397 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215968 0.84 TSHR (0.39) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL182724 0.72 LMNA (0.40) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL182752 0.72 TSHR (0.43) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL2931696 0.71 ALDH1A1 (0.54) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL6858168 0.70 TSHR (0.50) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL215969 0.69 TSHR (0.44) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL182493 0.68 MAPT (0.62) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL2930130 0.67 TSHR (0.48) ALDH1A1MAPK1TSHRMAPTLMNA
SCHEMBL182801 0.65 CYP1A2 (0.36) ALDH1A1MEN1KMT2AHTT
SCHEMBL12513703 0.64 ALDH1A1 (0.39) ALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465962-B1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIV FLORIDA (US) 2012-01-04 EP disclosed
EP-1465962-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2004-10-13 EP disclosed
US-6791738-B2 CONTROLLING COLOR, BRIGHTNESS AND ENVIRONMENTAL STABILITY; POLY- 3,4-ALKYLENEDIOXYHETEROCYCLES UNIVERSITY OF FLORIDA 2004-09-14 US disclosed
US-20030174377-A1 Electrochromic polymers and polymer electrochromic devices UNIVERSITY OF FLORIDA 2003-09-18 US disclosed
WO-2003046106-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2003-06-05 WO disclosed