SCHEMBL18275083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18275126	0.83	MEN1 (0.53)	SRD5A2RARBRARGMEN1CYP1A2
	SCHEMBL18275124	0.80	NR1I2 (0.49)	SRD5A2RARBRARGMEN1CYP1A2
	SCHEMBL18275080	0.79	SRD5A2 (0.46)	SRD5A2RARBRARGMEN1CYP1A2
	SCHEMBL18275128	0.78	SRD5A2 (0.45)	SRD5A2RARBMEN1CYP1A2KMT2A
	SCHEMBL18151473	0.77	AR (0.43)	EPHX2ARNR1H3ALDH1A1
	SCHEMBL448814	0.77	SHBG (0.59)	SRD5A2RARBRARGMEN1CYP1A2
	SCHEMBL2879876	0.77	SRD5A2 (0.55)	SRD5A2RARBRARGEPHX2NR1H4
	SCHEMBL1021804	0.77	SRD5A2 (0.55)	SRD5A2RARBRARGEPHX2NR1H4
	SCHEMBL18275085	0.76	SRD5A2 (0.44)	SRD5A2RARBRARGMEN1CYP1A2
	SCHEMBL18275129	0.75	PTPN1 (0.48)	SRD5A2CYP1A2RXRARXRBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.