Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475689 | 0.90 | FAAH (0.38) | FAAHCES1CTSA | |
| SCHEMBL1827574 | 0.83 | FAAH (0.36) | FAAHCES1CTSA | |
| SCHEMBL9452948 | 0.81 | CTSA (0.38) | CTSALMNAALOX5PPARGPPARA | |
| SCHEMBL4328044 | 0.77 | MEN1 (0.32) | FAAHCES1CTSA | |
| SCHEMBL4327553 | 0.76 | CTSA (0.41) | CTSA | |
| SCHEMBL31366797 | 0.75 | CA2 (0.37) | CA2MAPK1LMNAALOX5PPARG | |
| SCHEMBL9452969 | 0.74 | CYP1A2 (0.40) | CTSALMNA | |
| SCHEMBL14764834 | 0.73 | FAAH (0.36) | FAAHCES1 | |
| SCHEMBL22610222 | 0.73 | MAPK1 (0.41) | CA2MAPK1ALOX5PPARGPPARA | |
| SCHEMBL5504563 | 0.73 | SLC2A1 (0.37) | FAAHCES1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373264-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | Pfizer Limited (GB) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079200-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2002-10-10 | — | — | WO | disclosed |