Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.38 |
| ▸ | TUBB | P07437 | 5/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824781 | 0.89 | TUBB4A (0.44) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1824745 | 0.89 | TUBB4A (0.44) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1616061 | 0.85 | POLB (0.50) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3839280 | 0.81 | TUBB4A (0.44) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1825063 | 0.80 | TUBB4A (0.43) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1827155 | 0.78 | TUBB4A (0.42) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1823740 | 0.78 | TUBB4A (0.38) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1823476 | 0.78 | TUBB4A (0.41) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1826220 | 0.77 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4035604 | 0.77 | ACHE (0.40) | POLBTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |